Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18944664 | 0.68 | ATM (0.42) | LMNASMN1; SMN2HTR7PTBP1POLB | |
| SCHEMBL23904715 | 0.68 | MAOA (0.38) | LMNASMN1; SMN2HTR7PTBP1POLB | |
| SCHEMBL23958935 | 0.67 | MAOA (0.37) | LMNASMN1; SMN2HTR7PTBP1POLB | |
| SCHEMBL21653426 | 0.66 | LMNA (0.38) | HDAC3HDAC1HDAC2LMNASMN1; SMN2 | |
| SCHEMBL23905794 | 0.64 | MAOA (0.39) | LMNASMN1; SMN2HTR7PTBP1POLB | |
| SCHEMBL18809492 | 0.64 | LMNA (0.41) | LMNASMN1; SMN2HTR7PTBP1POLB | |
| SCHEMBL23905645 | 0.64 | ALDH1A1 (0.39) | LMNASMN1; SMN2HTR7PTBP1POLB | |
| SCHEMBL18290279 | 0.62 | PTGIR (0.44) | HDAC3HDAC1HDAC2LMNASMN1; SMN2 | |
| Alcohol SCHEMBL28041790 | 0.62 | ACHE (0.53) | LMNAHTR7CES2CES1ALDH1A1 | |
| SCHEMBL10413993 | 0.61 | MAOA (0.55) | LMNASMN1; SMN2HTR7PTBP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023084449-A1 | DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2023-05-19 | — | — | WO | disclosed |