Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574526 | 1.00 | RAPGEF4 (0.45) | RAPGEF4KCNK18APPP2RX1KCNJ6 | |
| SCHEMBL30574528 | 0.83 | RAPGEF4 (0.40) | RAPGEF4 | |
| SCHEMBL23908293 | 0.81 | TSHR (0.43) | MAPTALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL26895179 | 0.79 | RAPGEF4 (0.46) | RAPGEF4KCNK18APPP2RX1KCNJ6 | |
| SCHEMBL21625856 | 0.78 | KIF11 (0.54) | RAPGEF4KCNK18P2RX1KCNJ6KCNJ5 | |
| SCHEMBL29514710 | 0.78 | KIF11 (0.54) | RAPGEF4KCNK18P2RX1KCNJ6KCNJ5 | |
| SCHEMBL23908289 | 0.77 | NPSR1 (0.50) | BRD4KAT2BBRD9MAPTALDH1A1 | |
| SCHEMBL22343445 | 0.76 | KCNK18 (0.40) | KCNK18P2RX1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL22938476 | 0.75 | P2RX1 (0.47) | RAPGEF4KCNK18P2RX1KCNJ6KCNJ5 | |
| SCHEMBL26316048 | 0.75 | P2RX1 (0.50) | KCNK18APPP2RX1KCNJ6KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845768-B2 | Polycyclic compound and organic light-emitting device including same | LG CHEM, LTD. (KR) | 2023-12-19 | — | — | US | disclosed |
| US-20210317147-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | LG CHEM, LTD. (KR) | 2021-10-14 | — | — | US | disclosed |
| US-20210317147-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | LG CHEM, LTD. (KR) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317147-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | CYP1A1, CRY1, CYP1B1 | RAPGEF4 3984/4885KCNK18 1065/4885APP 823/4885 |
| US-11845768-B2 | Polycyclic compound and organic light-emitting device including same | CRY1, CYP1A1, CRY2 | RAPGEF4 3985/4885KCNK18 999/4885APP 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.