Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133330 | 0.78 | ENPP2 (0.50) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL23221434 | 0.75 | CA2 (0.46) | ENPP2KDM4EMGLLLPLLIPG | |
| SCHEMBL29951972 | 0.73 | ENPP2 (0.46) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL29956472 | 0.73 | ENPP2 (0.45) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL27195038 | 0.73 | ENPP2 (0.45) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL3110223 | 0.73 | ENPP2 (0.45) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL852507 | 0.73 | LPL (0.46) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL29952304 | 0.73 | LPL (0.46) | ENPP2KDM4EALDH1A1MGLLLPL | |
| SCHEMBL3785082 | 0.72 | MGLL (0.55) | ENPP2KDM4EALDH1A1MGLLCA4 | |
| SCHEMBL20171112 | 0.71 | ACHE (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |