Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 11/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904680 | 0.89 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23904679 | 0.89 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL18902791 | 0.80 | HTR1B (0.57) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23912992 | 0.79 | LTA4H (0.53) | ADRA1AADRA1DADRA1BKDM4EHTT | |
| SCHEMBL10030744 | 0.76 | AR (0.51) | KDM4EHTTALDH1A1LMNAMEN1 | |
| SCHEMBL23912947 | 0.74 | ADRA1D (0.38) | ADRA1AADRA1DADRA1BKDM4EALDH1A1 | |
| SCHEMBL3129427 | 0.71 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BHTR1AADRA2A | |
| SCHEMBL8088577 | 0.71 | L3MBTL1 (0.44) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23912875 | 0.70 | LTA4H (0.48) | ADRA1AADRA1DADRA1BKDM4EHTT | |
| SCHEMBL28288419 | 0.68 | MAPT (0.52) | KDM4EHTTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |