SCHEMBL23914283

SCHEMBL23914283

C=C1C(=O)O[C@H](c2ccccc2O)[C@@H]1c1cccc(C#N)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.39
CYP19A1 P11511 1/20 0.38
DRD2 P14416 2/20 0.36
DRD3 P35462 2/20 0.36
ABCC9 O60706 1/20 0.34
ABCC8 Q09428 1/20 0.34
KCNJ11 Q14654 1/20 0.34
KCNJ8 Q15842 1/20 0.34
HTR2B P41595 1/20 0.33
AR P10275 3/20 0.33
CXCR2 P25025 1/20 0.33
CYP3A4 P08684 1/20 0.33
XDH P47989 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
HSD11B1 P28845 1/20 0.33
AKR1C3 P42330 1/20 0.33
TBXA2R P21731 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23913797 0.82 ESR1 (0.39) LDHACYP19A1DRD2DRD3ABCC9
SCHEMBL23914339 0.82 STK10 (0.38) CYP19A1DRD2DRD3ARFADS1
SCHEMBL23914329 0.72 NPBWR1 (0.40) CYP19A1DRD2DRD3CYP3A4FADS1
SCHEMBL23914064 0.71 TNKS (0.34) CYP19A1CXCR2
SCHEMBL23914431 0.71 TNKS (0.40) CYP19A1ARFADS1
SCHEMBL23913791 0.71 TNKS (0.40) CYP19A1ARFADS1
SCHEMBL23913941 0.69 CA2 (0.46) CYP19A1AR
SCHEMBL30528399 0.65 ALDH1A1 (0.47) CYP19A1CYP3A4
SCHEMBL23913984 0.64 SMN1; SMN2 (0.39) CYP19A1HTR2BARCYP3A4ADORA3
SCHEMBL23914452 0.64 SMN1; SMN2 (0.39) CYP19A1HTR2BARCYP3A4ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS PURDUE RESEARCH FOUNDATION (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS MIF, LTA, MGAM LDHA 1347/4885CYP19A1 2911/4885DRD2 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.