SCHEMBL23913797

SCHEMBL23913797

C=C1C(=O)O[C@H](c2ccc(O)cc2)[C@@H]1c1cccc(C#N)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.39
ESR2 Q92731 1/20 0.39
LDHA P00338 1/20 0.38
FADS1 O60427 3/20 0.37
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
P4HB P07237 1/20 0.37
CYP19A1 P11511 1/20 0.37
ABCC9 O60706 1/20 0.35
ABCC8 Q09428 1/20 0.35
KCNJ11 Q14654 1/20 0.35
KCNJ8 Q15842 1/20 0.35
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
AR P10275 1/20 0.34
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23913941 0.87 CA2 (0.46) ESR1ESR2P4HBCYP19A1CA12
SCHEMBL23914283 0.82 LDHA (0.39) LDHAFADS1DRD2DRD3CYP19A1
SCHEMBL23914329 0.79 NPBWR1 (0.40) FADS1DRD2DRD3P4HBCYP19A1
SCHEMBL23914431 0.78 TNKS (0.40) FADS1CYP19A1ARMAOAMAOB
SCHEMBL23913791 0.78 TNKS (0.40) FADS1CYP19A1ARMAOAMAOB
SCHEMBL23914310 0.74 MAPK1 (0.37) FADS1CYP19A1ARMAOAMAOB
SCHEMBL23914317 0.73 MAOB (0.39) FADS1CYP19A1CA2ARMAOA
SCHEMBL23913790 0.73 ALDH1A1 (0.46) FADS1CYP19A1
SCHEMBL23914279 0.73 ALDH1A1 (0.46) FADS1CYP19A1
SCHEMBL23914452 0.69 SMN1; SMN2 (0.39) CYP19A1CA2ARMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS PURDUE RESEARCH FOUNDATION (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317099-A1 SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS MIF, LTA, MGAM ESR1 3952/4885ESR2 4288/4885LDHA 1347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.