Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497618 | 0.74 | CYP3A4 (0.39) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL5501432 | 0.74 | POLB (0.42) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL2269866 | 0.74 | KDM4E (0.47) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL4429415 | 0.72 | PAX8 (0.48) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL29951410 | 0.69 | ERN1 (0.47) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL2265534 | 0.69 | KCNA3 (0.34) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL3860557 | 0.69 | ALDH1A1 (0.44) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL19783244 | 0.69 | KCNA3 (0.55) | ALDH1A1CYP3A4HPGDKDM4EHSD17B10 | |
| SCHEMBL6194067 | 0.69 | ERN1 (0.47) | ALDH1A1CYP3A4HPGDKDM4EMEN1 | |
| SCHEMBL275378 | 0.68 | MAOA (0.45) | ALDH1A1CYP3A4HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317109-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317109-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | CRBN, CLNS1A, ADRM1 | ALDH1A1 2347/4885CYP3A4 4280/4885HPGD 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.