SCHEMBL23919370

SCHEMBL23919370

c1ccc2cc3c(cc2c1)oc1cccc(-c2c4ccccc4c(-c4ccc(-c5ccc6oc7ccccc7c6c5)cc4)c4ccccc24)c13

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
AHR P35869 2/20 0.37
NPC1 O15118 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
PLA2G2A P14555 3/20 0.36
PLA2G4A P47712 3/20 0.36
ALOX5 P09917 1/20 0.36
CASP3 P42574 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
PLA2G10 O15496 1/20 0.34
CHEK2 O96017 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22548027 0.95 CASP3 (0.38) MAPTAHRNPC1KDM4EMEN1
SCHEMBL22544913 0.95 MAPT (0.39) MAPTAHRNPC1KDM4EMEN1
SCHEMBL23919369 0.94 PLA2G2A (0.39) MAPTAHRNPC1KDM4EMEN1
SCHEMBL23746879 0.94 PLA2G2A (0.40) MAPTAHRNPC1KDM4EMEN1
SCHEMBL27341824 0.94 ALOX5 (0.38) MAPTAHRNPC1KDM4EMEN1
SCHEMBL23426936 0.94 MAPT (0.36) MAPTAHRNPC1KDM4EMEN1
SCHEMBL22545071 0.94 MAPT (0.36) MAPTAHRNPC1KDM4EMEN1
SCHEMBL23428141 0.93 ESR1 (0.38) MAPTAHRNPC1KDM4EMEN1
SCHEMBL22063120 0.91 MAPT (0.36) MAPTAHRNPC1KDM4EMEN1
SCHEMBL22545073 0.90 PLA2G2A (0.38) MAPTAHRNPC1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-05-26 US disclosed
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 MAPT 2477/4885AHR 1116/4885NPC1 3340/4885
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME LEF1, OR10J3, RER1 MAPT 2275/4885AHR 4268/4885NPC1 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.