SCHEMBL23919975

SCHEMBL23919975

Cc1cc(C(c2ccc(O)cc2)c2cc(C)c(O)cc2O)c(O)cc1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.42
TRPA1 O75762 2/20 0.42
CACNA1C Q13936 1/20 0.42
ESR1 P03372 5/20 0.40
ESR2 Q92731 4/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
MAPT P10636 2/20 0.40
CYP2C9 P11712 2/20 0.40
ALOX15 P16050 2/20 0.40
CYP2C19 P33261 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
G6PD P11413 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
CCR6 P51684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278773 0.89 CYP1A2 (0.45) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL13416158 0.87 CYP1A2 (0.43) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL12005179 0.84 CYP3A4 (0.41) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL278739 0.82 TYR (0.44) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL278561 0.82 CYP2D6 (0.50) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL2464369 0.80 ESR1 (0.43) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL25998110 0.80 LMNA (0.45) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL18888468 0.80 TP53 (0.40) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL16859729 0.79 ESR1 (0.46) PTGS1TRPA1CACNA1CESR1ESR2
SCHEMBL4055460 0.78 ESR1 (0.41) PTGS1TRPA1CACNA1CESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2023-02-07 US disclosed
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component BRIX1, RBX1, HAX1 PTGS1 1507/4885TRPA1 865/4885CACNA1C 1632/4885
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT BRIX1, HAX1, RBX1 PTGS1 1529/4885TRPA1 822/4885CACNA1C 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.