SCHEMBL852873

SCHEMBL852873

CCCCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
TDP1 Q9NUW8 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.49
HCAR2 Q8TDS4 3/20 0.47
HPGD P15428 1/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
HSP90AA1 P07900 1/20 0.45
TP53 P04637 1/20 0.45
HSD17B10 Q99714 1/20 0.44
LMNA P02545 1/20 0.44
APP P05067 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392064 0.90 LMNA (0.50) TSHRTDP1L3MBTL1HCAR2HPGD
SCHEMBL65066 0.83 HSP90AA1 (0.50) TSHRATMHCAR2ALDH1A1HSP90AA1
Hydrochloric Acid SCHEMBL9061399 0.82 HSP90AA1 (0.49) TSHRATMALDH1A1HSP90AA1LMNA
Bromide SCHEMBL6879691 0.82 HSP90AA1 (0.49) TSHRATMHCAR2ALDH1A1HSP90AA1
SCHEMBL6290042 0.81 HSP90AA1 (0.47) TSHRTDP1L3MBTL1HCAR2ALDH1A1
SCHEMBL22124863 0.80 HSP90AA1 (0.44) TSHRTDP1L3MBTL1HCAR2ALDH1A1
SCHEMBL10467637 0.79 TSHR (0.45) TSHRHCAR2ALDH1A1CYP3A4HSP90AA1
SCHEMBL7907406 0.77 HSP90AA1 (0.54) TSHRL3MBTL1HCAR2ALDH1A1MAPK1
SCHEMBL12820596 0.77 TDP1 (0.45) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL2597946 0.76 ALDH1A1 (0.49) TSHRHPGDALDH1A1HSP90AA1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025201636-A1 PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 WO disclosed
EP-4504265-A1 PEG-LIPIDS AND LIPID NANOPARTICLES Capstan Therapeutics, Inc. (US) 2025-02-12 EP disclosed
WO-2023196445-A1 PEG-LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
WO-2021215900-A1 METHOD FOR PRODUCING BENZOPYRANONE COMPOUND AND NOVEL INTERMEDIATE USED THEREIN (주)아이랩 (KR) 2021-10-28 WO disclosed
US-11084826-B2 RSV antiviral pyrazolo- and triazolo-pyrimidine compounds Janssen Sciences Ireland Unlimited Company (IE) 2021-08-10 US disclosed
US-20200223855-A1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2020-07-16 US disclosed
US-20190248793-A1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2019-08-15 US disclosed
US-10208048-B2 RSV antiviral pyrazolo- and triazolo-pyrimidine compounds JANSSEN SCIENCES IRELAND UC (IE) 2019-02-19 US disclosed
US-20180105529-A1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS JANSSEN SCIENCES IRELAND UC (IE) 2018-04-19 US disclosed
US-9902725-B2 Heterocyclic derivatives as RORgamma modulators GENFIT (FR) 2018-02-27 US disclosed
WO-2005085197-A1 CYCLOBUTENEDIONE GROUPS-CONTAINING COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE SCHERING CORPORATION (US) 2005-09-15 WO disclosed
EP-1169323-A1 BETA-LACTAMASE INHIBITING COMPOUNDS Research Corporation Technologies, Inc (US) 2002-01-09 EP disclosed
WO-2000063213-A1 BETA-LACTAMASE INHIBITING COMPOUNDS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2000-10-26 WO disclosed
EP-0900197-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1999-03-10 EP disclosed
WO-1997030027-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1997-08-21 WO disclosed
EP-0755384-A1 CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES GLAXO WELLCOME INC. (US) 1997-01-29 EP disclosed
WO-1995028391-A1 CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES GLAXO WELLCOME INC. (US) 1995-10-26 WO disclosed
EP-0098629-B1 ANTI-COAGULANTS OF THE 4-HYDROXYCOUMARIN TYPE, THE PREPARATION THEREOF, AND RODENTICIDAL COMPOSITIONS (BAITS) COMPRISING SUCH ANTI-COAGULANTS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-08-26 EP disclosed
US-4520007-A Anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions (baits) comprising such anti-coagulants SHELL OIL COMPANY (US) 1985-05-28 US disclosed
EP-0098629-A1 Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208048-B2 RSV antiviral pyrazolo- and triazolo-pyrimidine compounds ZC3HAV1, MAVS, TYMP TSHR 2358/4885TDP1 1647/4885L3MBTL1 4807/4885
US-20200223855-A1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS ZC3HAV1, MAVS, TYMP TSHR 2358/4885TDP1 1647/4885L3MBTL1 4807/4885
US-11084826-B2 RSV antiviral pyrazolo- and triazolo-pyrimidine compounds ZC3HAV1, MAVS, TYMP TSHR 2358/4885TDP1 1647/4885L3MBTL1 4807/4885
US-20180105529-A1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS ZC3HAV1, MAVS, TYMP TSHR 2358/4885TDP1 1647/4885L3MBTL1 4807/4885
US-20190248793-A1 RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS ZC3HAV1, MAVS, TYMP TSHR 2358/4885TDP1 1647/4885L3MBTL1 4807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.