SCHEMBL23924659

SCHEMBL23924659

CC(N)CC(C)CC(C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.54
GABRR1 P24046 2/20 0.44
SLC7A5 Q01650 2/20 0.44
FOLH1 Q04609 2/20 0.43
NAALAD2 Q9Y3Q0 2/20 0.43
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 1/20 0.40
LTA4H P09960 1/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19292743 0.87
SCHEMBL5147101 0.87
SCHEMBL23499736 0.87 NAALAD2 (0.52) ENPEPGABRR1SLC7A5FOLH1NAALAD2
Hydrochloric Acid SCHEMBL30319513 0.85 ENPEP (0.58) ENPEPGABRR1SLC7A5FOLH1NAALAD2
Hydrochloric Acid SCHEMBL30319514 0.85 ENPEP (0.58) ENPEPGABRR1SLC7A5FOLH1NAALAD2
SCHEMBL23499629 0.85 NAALAD2 (0.50) ENPEPGABRR1SLC7A5FOLH1NAALAD2
SCHEMBL23943308 0.81 ALDH1A1 (0.38) ENPEPGABRR1SLC7A5SLC1A3SLC1A2
SCHEMBL4213397 0.80 RNPEP (0.48) ENPEPGABRR1SLC7A5FOLH1NAALAD2
SCHEMBL11491423 0.78 GABRR1 (0.52) ENPEPGABRR1SLC7A5FOLH1NAALAD2
SCHEMBL2868545 0.78 GABRR1 (0.52) ENPEPGABRR1SLC7A5FOLH1NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021186-A1 Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-01-22 US claimed
EP-4565325-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-06-11 EP claimed
CN-119855613-A Fatty acid-D-amino acid peptide conjugates as anaplerotic compounds for the treatment of hyperuricemia, methylmalonic urine disorder and energy metabolism disorders 匹兹堡大学高等教育联邦体系 2025-04-18 CN claimed
WO-2024030367-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2024-02-08 WO claimed
US-20260021186-A1 Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-01-22 US disclosed
EP-4565325-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-06-11 EP disclosed
CN-119855613-A Fatty acid-D-amino acid peptide conjugates as anaplerotic compounds for the treatment of hyperuricemia, methylmalonic urine disorder and energy metabolism disorders 匹兹堡大学高等教育联邦体系 2025-04-18 CN disclosed
US-12213956-B2 Method of treating fatty acid oxidation disorders using omega3/omega6 unsaturated or branched chain fatty acids University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-02-04 US disclosed
WO-2024030367-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2024-02-08 WO disclosed
US-11844775-B2 Method of treating fatty acid oxidation disorders using Omega3/Omega6 unsaturated or branched chain fatty acids University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-12-19 US disclosed
US-20210353581-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2021-11-18 US disclosed
US-20210322357-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210353581-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids ELOVL6, ELOVL3, CPT1B ENPEP 984/4885GABRR1 1462/4885SLC7A5 721/4885
US-11844775-B2 Method of treating fatty acid oxidation disorders using Omega3/Omega6 unsaturated or branched chain fatty acids ELOVL6, ELOVL3, CPT1B ENPEP 965/4885GABRR1 1485/4885SLC7A5 698/4885
US-20260021186-A1 Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders HADHB, HADHA, HADH ENPEP 360/4885GABRR1 589/4885SLC7A5 175/4885
US-20210322357-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids ELOVL6, ELOVL3, CPT1B ENPEP 965/4885GABRR1 1485/4885SLC7A5 698/4885
US-12213956-B2 Method of treating fatty acid oxidation disorders using omega3/omega6 unsaturated or branched chain fatty acids ELOVL6, ELOVL3, CPT1B ENPEP 984/4885GABRR1 1462/4885SLC7A5 721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.