Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515296 | 1.00 | TBXAS1 (0.48) | TBXAS1EPHX2PPARGCYP3A4CYP2C9 | |
| SCHEMBL2392661 | 0.87 | KMT2A (0.47) | TBXAS1ESR1MEN1KMT2A | |
| SCHEMBL1907796 | 0.86 | DPEP1 (0.49) | TBXAS1EPHX2PPARGESR1PSEN1 | |
| SCHEMBL2394174 | 0.86 | DPEP1 (0.49) | TBXAS1EPHX2PPARGESR1PSEN1 | |
| SCHEMBL5173409 | 0.86 | TBXAS1 (0.58) | TBXAS1EPHX2PPARGCYP3A4CYP2C9 | |
| SCHEMBL4218085 | 0.84 | LMNA (0.51) | TBXAS1EPHX2PPARGCYP3A4CYP2C9 | |
| SCHEMBL5613678 | 0.84 | LMNA (0.51) | TBXAS1EPHX2PPARGCYP3A4CYP2C9 | |
| SCHEMBL2389154 | 0.83 | PSEN1 (0.51) | CYP3A4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12499859 | 0.81 | ALDH1A1 (0.41) | TBXAS1CYP3A4CYP2C9PSEN1PSEN2 | |
| SCHEMBL12499866 | 0.81 | ALDH1A1 (0.41) | TBXAS1CYP3A4CYP2C9PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |