Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 known ✓ | P08588 | 3/20 | 0.33 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.33 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278267 | 0.98 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Hydrochloric Acid SCHEMBL170004 | 0.96 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Bromide SCHEMBL9662608 | 0.96 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Iodide SCHEMBL8165516 | 0.96 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Hydrochloric Acid SCHEMBL11567894 | 0.95 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Acetic Acid SCHEMBL11274105 | 0.89 | ELANE (0.40) | GABRA1GABRB2ALDH1A1ELANETSHR | |
| SCHEMBL6841870 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| SCHEMBL2003722 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Iodide SCHEMBL19307326 | 0.81 | GABRA1 (0.36) | GABRA1GABRB2ALDH1A1ELANEADRB2 | |
| Hydrochloric Acid SCHEMBL859874 | 0.81 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1LMNAADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809157-B2 | Methods of forming a programmable region that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion | MICRON TECHNOLOGY, INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-8633084-B1 | Methods of forming a memory cell having programmable material that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion | MICRON TECHNOLOGY, INC. (US) | 2014-01-21 | — | — | US | claimed |
| US-8024943-B2 | Method of dividing glass into separate pieces with the aid of a cutting liquid and improved cutting liquid for said method | SCHOTT AG (DE) | 2011-09-27 | — | — | US | claimed |
| US-20060266195-A1 | Method of dividing glass into separate pieces with the aid of a cutting liquid and improved cutting liquid for said method | SCHOTT AG (DE) | 2006-11-30 | — | — | US | claimed |
| CN-115895631-A | Pressure-reducing injection-increasing surfactant composition and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2020203345-A1 | COATING STRIPPING AGENT AND COATING STRIPPING METHOD | 王子ホールディングス株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-8809157-B2 | Methods of forming a programmable region that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion | MICRON TECHNOLOGY, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-8633084-B1 | Methods of forming a memory cell having programmable material that comprises a multivalent metal oxide portion and an oxygen containing dielectric portion | MICRON TECHNOLOGY, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-8024943-B2 | Method of dividing glass into separate pieces with the aid of a cutting liquid and improved cutting liquid for said method | SCHOTT AG (DE) | 2011-09-27 | — | — | US | disclosed |
| US-20060266195-A1 | Method of dividing glass into separate pieces with the aid of a cutting liquid and improved cutting liquid for said method | SCHOTT AG (DE) | 2006-11-30 | — | — | US | disclosed |