Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23235736 | 0.85 | GRM5 (0.48) | MEN1NPC1MAPTKMT2AGRM5 | |
| SCHEMBL23235685 | 0.83 | L3MBTL1 (0.45) | MEN1NPC1MAPTKMT2AGRM5 | |
| SCHEMBL30676101 | 0.83 | L3MBTL1 (0.45) | MEN1NPC1MAPTKMT2AGRM5 | |
| SCHEMBL28543738 | 0.83 | P2RX7 (0.43) | — | |
| SCHEMBL23929009 | 0.83 | GPR119 (0.51) | MEN1NPC1MAPTKMT2AGRM5 | |
| SCHEMBL30269629 | 0.81 | NPC1 (0.46) | MEN1NPC1MAPTKMT2AGRM5 | |
| SCHEMBL23235689 | 0.81 | HTR1A (0.55) | — | |
| SCHEMBL30676112 | 0.81 | HTR1A (0.55) | — | |
| SCHEMBL25088370 | 0.80 | GRM5 (0.39) | MEN1NPC1MAPTKMT2AGRM5 | |
| SCHEMBL28545272 | 0.79 | KCNH2 (0.41) | KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566637-B | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-112566637-A | GLP-1 receptor agonists and uses thereof | 辉瑞公司 | 2021-03-26 | — | — | CN | disclosed |