Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929240 | 1.00 | GPR52 (0.56) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL14571875 | 0.82 | GPR52 (0.58) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL28945946 | 0.82 | GPR52 (0.58) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL6207002 | 0.81 | GPR52 (0.53) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL6990805 | 0.81 | GPR52 (0.49) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL6990808 | 0.81 | GPR52 (0.49) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL3638330 | 0.81 | ALDH1A1 (0.62) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL17429280 | 0.79 | ALDH1A1 (0.66) | GPR52KEAP1ALDH1A1FFAR1MAPT | |
| SCHEMBL1062338 | 0.79 | L3MBTL1 (0.49) | GPR52KEAP1ALDH1A1MAPTTDP1 | |
| SCHEMBL1062335 | 0.79 | L3MBTL1 (0.49) | GPR52KEAP1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139275-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021213500-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-10-28 | — | — | WO | disclosed |