Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930016 | 0.77 | CYP1A2 (0.45) | ALDH1A1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL15079366 | 0.71 | KDM4E (0.44) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15079775 | 0.69 | MAPT (0.39) | ALDH1A1HPGDLMNANPSR1NPC1 | |
| SCHEMBL10097089 | 0.68 | DRD2 (0.36) | ALDH1A1DRD2DRD4DRD3KCNH2 | |
| SCHEMBL15079895 | 0.68 | ATF4 (0.40) | ALDH1A1DRD2DRD4DRD3HPGD | |
| SCHEMBL15079886 | 0.68 | LMNA (0.39) | ALDH1A1KCNH2LMNANPC1RAB9A | |
| SCHEMBL15079880 | 0.68 | LTA4H (0.43) | SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL15079756 | 0.68 | KMT2A (0.39) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15079913 | 0.68 | GAA (0.41) | DRD2DRD4LMNARAB9ATDP1 | |
| SCHEMBL13724052 | 0.68 | HPGD (0.43) | ALDH1A1DRD2DRD4DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |