SCHEMBL15079880

SCHEMBL15079880

Oc1ccccc1C1(COc2ccc(Oc3ccccc3)cc2)CC1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
PLA2G2A P14555 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 1/20 0.38
MAOB P27338 1/20 0.37
AOC3 Q16853 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
PNLIP P16233 1/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15079886 0.88 LMNA (0.39) LTA4HSMN1; SMN2HRH3
SCHEMBL15079366 0.84 KDM4E (0.44) LTA4HSMN1; SMN2TSHRPOLB
SCHEMBL15079895 0.84 ATF4 (0.40) TSHRPOLB
SCHEMBL15079426 0.84 CYP26A1 (0.34) SMN1; SMN2MAOB
SCHEMBL15079790 0.84 PKM (0.51) TSHR
SCHEMBL15079779 0.82 MAOB (0.44) SMN1; SMN2TSHRMAOBHRH3
SCHEMBL15079775 0.82 MAPT (0.39) SMN1; SMN2L3MBTL1
SCHEMBL15079856 0.81 MEN1 (0.45) MAOBAOC3L3MBTL1
SCHEMBL15079756 0.81 KMT2A (0.39) SMN1; SMN2POLBL3MBTL1
SCHEMBL15079849 0.81 SMN1; SMN2 (0.42) SMN1; SMN2TSHRMAOBAOC3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 LTA4H 273/4885NR1H2 555/4885BAX 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.