SCHEMBL15079366

SCHEMBL15079366

CCOc1ccc(OCC2(c3ccccc3O)CC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
NQO1 P15559 1/20 0.44
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 2/20 0.43
TP53 P04637 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 2/20 0.43
HTT P42858 1/20 0.43
LTA4H P09960 2/20 0.43
GAA P10253 1/20 0.43
RELA Q04206 1/20 0.40
PDK2 Q15119 2/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.40
BACE1 P56817 1/20 0.40
POLB P06746 1/20 0.38
MAPK1 P28482 1/20 0.38
APOBEC3A P31941 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15079775 0.88 MAPT (0.39) KDM4ENPC1RAB9AKMT2ALMNA
SCHEMBL15079886 0.84 LMNA (0.39) NPC1RAB9ALMNASMN1; SMN2LTA4H
SCHEMBL15079880 0.84 LTA4H (0.43) SMN1; SMN2LTA4HPOLBTSHR
SCHEMBL15079895 0.84 ATF4 (0.40) NPC1RAB9AKMT2AMEN1MAPT
SCHEMBL15079771 0.84 TDP1 (0.47) NPC1RAB9AKMT2ALMNATP53
SCHEMBL15079849 0.84 SMN1; SMN2 (0.42) KDM4ENPC1RAB9AKMT2ALMNA
SCHEMBL15079756 0.84 KMT2A (0.39) KDM4ENPC1RAB9AKMT2ALMNA
SCHEMBL15079876 0.83 HRH3 (0.41) NPC1RAB9AMAPT
SCHEMBL15079779 0.82 MAOB (0.44) KMT2ASMN1; SMN2MEN1MAPTALDH1A1
SCHEMBL15079426 0.81 CYP26A1 (0.34) KMT2ALMNASMN1; SMN2MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 KDM4E 598/4885NQO1 11/4885NPC1 2259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.