Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395647 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL11450513 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL8372059 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL6454626 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL8372056 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL3039631 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL11450516 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL4122071 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL4130338 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 | |
| SCHEMBL4122070 | 1.00 | FAAH (0.48) | FAAHTRPV1TSHRTERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200121652-A1 | COMPOUNDS HAVING CASPASE INHIBITORY ACTIVITY, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS AND FOR TREATING OR PREVENTING CORNEAL ENDOTHELIAL SYMPTOMS, DISORDERS, OR DISEASES, AND APPLICATION OF SAID PHARMACEUTICAL AGENT | THE DOSHISHA (JP) | 2020-04-23 | — | — | US | disclosed |
| EP-3639855-A1 | COMPOUNDS HAVING CASPASE INHIBITORY ACTIVITY, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS AND FOR TREATING OR PREVENTING CORNEAL ENDOTHELIAL SYMPTOMS, DISORDERS, OR DISEASES, AND APPLICATION OF SAID PHARMACEUTICAL AGENT | The Doshisha (JP) | 2020-04-22 | — | — | EP | disclosed |
| US-9029572-B2 | 3-hydroxy-6H-benzo [C] chromene-6-one derivative and manufacturing method thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-8975256-B2 | 1,2,3,4-tetrahydroquinoxaline compounds having glucocorticoid receptor binding activity | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2015-03-10 | — | — | US | disclosed |
| US-20140296540-A1 | 3-HYDROXY-6H-BENZO [C] CHROMENE-6-ONE DERIVATIVE AND MANUFACTURING METHOD THEREOF | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-8802869-B2 | 3-hydroxy-6H-benzo [c] chromene-6-one derivative and manufacturing method thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2674422-A1 | 3-HYDROXY-6H-BENZO[C]CHROMEN-6-ONE DERIVATIVE AND METHOD FOR PRODUCING SAME | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2013-12-18 | — | — | EP | disclosed |
| EP-1944290-B1 | NOVEL 1-2-DIHYDROQUINOLINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2013-12-04 | — | — | EP | disclosed |
| US-20130310576-A1 | 3-HYDROXY-6H-BENZO [C] CHROMENE-6-ONE DERIVATIVE AND MANUFACTURING METHOD THEREOF | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2013-11-21 | — | — | US | disclosed |
| US-20130303537-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE COMPOUNDS HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2013-11-14 | — | — | US | disclosed |
| EP-1316610-A1 | Preparation comprising an enzyme for asymmetrical hydrolysis of N-substituted C3-C4 cyclic imino-2-carboxylic acid ester and method of using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-20030091931-A1 | Benzbisazole compound and optical recording medium containing the compound | MITSUI CHEMICALS, INC. (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1262966-A2 | Optical recording medium and novel azaporphyrin compound | Mitsui Chemicals, Inc. (JP) | 2002-12-04 | — | — | EP | disclosed |
| EP-1247655-A1 | OPTICAL RECORDING MEDIUM AND NOVEL AZAPORPHYRIN COMPOUNDS | Mitsui Chemicals, Inc. (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-1245571-A1 | BENZBISAZOLE COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-1180765-A1 | Optical recording medium and porphycene compound | Mitsui Chemicals, Inc. (JP) | 2002-02-20 | — | — | EP | disclosed |
| US-5856521-A | Acrylic or methacrylic acid derivatives and polymers obtained therefrom | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0449049-B1 | Naphthalenedicarboxylic acid esters | HOFFMANN LA ROCHE (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5230828-A | NAPHTHALENEDICARBOXYLIC ACID ESTERS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0449049-A2 | Naphthalenedicarboxylic acid esters | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296540-A1 | 3-HYDROXY-6H-BENZO [C] CHROMENE-6-ONE DERIVATIVE AND MANUFACTURING METHOD THEREOF | CYP8B1, CTRC, CYP7B1 | FAAH 2439/4885TRPV1 3229/4885TSHR 2795/4885 |
| US-20030091931-A1 | Benzbisazole compound and optical recording medium containing the compound | DAO, CACNA1I, KCNB2 | FAAH 1285/4885TRPV1 122/4885TSHR 3514/4885 |
| US-20130310576-A1 | 3-HYDROXY-6H-BENZO [C] CHROMENE-6-ONE DERIVATIVE AND MANUFACTURING METHOD THEREOF | CYP8B1, CTRC, CYP7B1 | FAAH 2439/4885TRPV1 3229/4885TSHR 2795/4885 |
| US-20200121652-A1 | COMPOUNDS HAVING CASPASE INHIBITORY ACTIVITY, PHARMACEUTICAL AGENT CONTAINING SAID COMPOUNDS AND FOR TREATING OR PREVENTING CORNEAL ENDOTHELIAL SYMPTOMS, DISORDERS, OR DISEASES, AND APPLICATION OF SAID PHARMACEUTICAL AGENT | TGFB1, CASP3, TGFB2 | FAAH 1856/4885TRPV1 2942/4885TSHR 4706/4885 |
| US-20130303537-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE COMPOUNDS HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | NR3C1, NR3C2, NR5A1 | FAAH 3276/4885TRPV1 2340/4885TSHR 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.