Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | PDE5A | O76074 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036385 | 0.83 | PARP1 (0.38) | PARP1PDE5ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL9036389 | 0.83 | PARP1 (0.38) | PARP1PDE5ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL9034715 | 0.81 | PARP1 (0.48) | PARP1CYP1A2CYP1A1CYP1B1KDM4E | |
| SCHEMBL6199833 | 0.78 | PARP1 (0.66) | PARP1HTR3A | |
| SCHEMBL6982697 | 0.70 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL23959783 | 0.69 | CYP1A2 (0.44) | CYP1A2ALDH1A1KMT2APOLBHPGD | |
| SCHEMBL9035190 | 0.68 | PARP1 (0.41) | PARP1ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL8824023 | 0.68 | PARP1 (0.68) | PARP1HTR3A | |
| SCHEMBL6971863 | 0.66 | ALDH1A1 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL423080 | 0.66 | PARP1 (0.56) | PARP1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5151431-A | Diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |