Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 17/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307578 | 0.82 | RAB9A (0.52) | LMNATBXAS1 | |
| SCHEMBL25095623 | 0.82 | KDM4E (0.34) | TNF | |
| SCHEMBL29852373 | 0.82 | TNF (0.47) | TNFLMNATBXAS1CYP1A2 | |
| SCHEMBL23320277 | 0.79 | TBXAS1 (0.42) | TBXAS1CYP1A2 | |
| SCHEMBL14177830 | 0.77 | CYP1A2 (0.48) | TNFLMNACYP1A2 | |
| SCHEMBL2962862 | 0.76 | LMNA (0.50) | TNFLMNATBXAS1 | |
| SCHEMBL27772950 | 0.74 | CPB2 (0.40) | LMNATBXAS1CYP1A2 | |
| SCHEMBL11571898 | 0.73 | CPB2 (0.47) | TNFLMNACYP1A2 | |
| SCHEMBL8104641 | 0.73 | FAAH (0.53) | TNFTBXAS1 | |
| SCHEMBL29668401 | 0.73 | TBXAS1 (0.43) | LMNATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213445-A1 | SULTAM DERIVATIVES AND APPLICATION THEREOF | 南京明德新药研发有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |