SCHEMBL23960606

SCHEMBL23960606

CS(=O)(=O)N1C[C@H](Oc2ccc(CN)cc2)C[C@H](c2ccccc2)C1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RORC P51449 4/20 0.43
MMP3 P08254 1/20 0.37
PAX8 Q06710 1/20 0.37
FFAR4 Q5NUL3 9/20 0.36
KDM1A O60341 2/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932385 1.00 RORC (0.43) RORCMMP3PAX8FFAR4KDM1A
Trifluoroacetic Acid SCHEMBL23932458 0.92 TPSAB1 (0.42) RORCMMP3FFAR4
SCHEMBL23960572 0.90 RORC (0.37) RORCPAX8
SCHEMBL23932369 0.90 RORC (0.37) RORCPAX8
SCHEMBL23932460 0.85 MMP3 (0.41) RORCMMP3FFAR4ALDH1A1HRH3
SCHEMBL23960553 0.83 PDE4B (0.35) RORCPAX8KDM1A
SCHEMBL26078655 0.83 PDE4B (0.35) RORCPAX8KDM1A
SCHEMBL23932328 0.83 PDE4B (0.35) RORCPAX8KDM1A
SCHEMBL23960607 0.79 NAMPT (0.42) RORCMMP3
SCHEMBL30151664 0.79 NAMPT (0.42) RORCMMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
WO-2021216592-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 RORC 2781/4885MMP3 79/4885PAX8 3085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.