SCHEMBL23960607

SCHEMBL23960607

CC(C)(C)OC(=O)NCc1ccc(O[C@@H]2C[C@H](c3ccccc3)CN(S(C)(=O)=O)C2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.42
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
HDAC1 Q13547 2/20 0.38
MCL1 Q07820 7/20 0.38
BRD9 Q9H8M2 1/20 0.37
BAZ2B Q9UIF8 1/20 0.37
BAZ2A Q9UIF9 1/20 0.37
MMP3 P08254 1/20 0.37
HSD17B10 Q99714 1/20 0.37
RORC P51449 2/20 0.37
TACR1 P25103 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TLR2 O60603 1/20 0.37
TLR1 Q15399 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30636567 1.00 NAMPT (0.42) NAMPTCA12CA1CA7CA14
SCHEMBL30151664 1.00 NAMPT (0.42) NAMPTCA12CA1CA7CA14
SCHEMBL23932460 0.90 MMP3 (0.41) CA1MMP3HSD17B10RORCKMT2A
SCHEMBL23960541 0.81 NAMPT (0.44) NAMPTCA12CA1CA7CA14
SCHEMBL23960606 0.79 RORC (0.43) MMP3RORC
SCHEMBL23932385 0.79 RORC (0.43) MMP3RORC
Trifluoroacetic Acid SCHEMBL23932458 0.79 TPSAB1 (0.42) MMP3RORCKMT2A
SCHEMBL30151659 0.78 NAMPT (0.42) NAMPTCA12CA1CA7CA14
SCHEMBL26078689 0.78 NAMPT (0.42) NAMPTCA12CA1CA7CA14
SCHEMBL10233014 0.72 ALDH1A1 (0.52) NAMPTHDAC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
WO-2021216592-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 NAMPT 865/4885CA12 2912/4885CA1 2842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.