SCHEMBL23964231

SCHEMBL23964231

c1cc(CN2CCN(c3ccncc3)CC2)c2cc[nH]c2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DRD4 P21917 8/20 0.55
▸ DRD2 P14416 6/20 0.55
▸ DRD3 P35462 6/20 0.55
▸ GAA P10253 3/20 0.55
▸ MAPT P10636 2/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ LMNA P02545 3/20 0.49
▸ HTT P42858 2/20 0.49
▸ TSHR P16473 2/20 0.49
▸ POLB P06746 1/20 0.49
▸ CYP2D6 P10635 2/20 0.47
▸ BCHE P06276 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ PIK3CD O00329 1/20 0.43
▸ HTR2A P28223 1/20 0.42
▸ HTR7 P34969 1/20 0.42
▸ HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964192 0.83 DRD4 (0.80) DRD4DRD2DRD3GAAL3MBTL1
SCHEMBL23932511 0.80 HTR1A (0.47) DRD4DRD2DRD3GAAMAPT
SCHEMBL3622506 0.79 LMNA (0.58) DRD4DRD2DRD3GAAMAPT
SCHEMBL23432525 0.78 GAA (0.52) DRD4DRD2DRD3GAAMAPT
SCHEMBL13284389 0.78 KDM4E (0.65) DRD4DRD2DRD3GAAMAPT
SCHEMBL30099664 0.76 HTR6 (0.56) DRD4DRD2DRD3GAAMAPT
SCHEMBL23609411 0.76 HTR6 (0.56) DRD4DRD2DRD3GAAMAPT
SCHEMBL30040708 0.73 PARP1 (0.52) DRD4DRD2MAPTPOLBKDM4E
SCHEMBL23932588 0.73 PARP1 (0.52) DRD4DRD2MAPTPOLBKDM4E
SCHEMBL31370877 0.72 DRD4 (0.75) DRD4DRD2DRD3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 — — CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 — — CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 — — CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 — — WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 DRD4 4746/4885DRD2 4780/4885DRD3 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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