Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609411 | 1.00 | HTR6 (0.56) | HTR6ADRB1GAAMAPTBCHE | |
| SCHEMBL3622506 | 0.87 | LMNA (0.58) | HTR6ADRB1GAAMAPTBCHE | |
| SCHEMBL13284389 | 0.86 | KDM4E (0.65) | HTR6GAAMAPTBCHECYP2D6 | |
| SCHEMBL23432525 | 0.83 | GAA (0.52) | GAAMAPTBCHECYP2D6LMNA | |
| SCHEMBL948663 | 0.79 | CYP2D6 (0.81) | HTR6GAABCHECYP2D6LMNA | |
| SCHEMBL32691857 | 0.78 | GAA (0.50) | HTR6GAAMAPTBCHECYP2D6 | |
| SCHEMBL28256631 | 0.77 | OPRM1 (0.55) | GAAMAPTBCHECYP2D6LMNA | |
| SCHEMBL27854002 | 0.77 | LMNA (0.47) | HTR6ADRB1GAAMAPTBCHE | |
| SCHEMBL23964231 | 0.76 | DRD4 (0.55) | HTR6GAAMAPTBCHECYP2D6 | |
| SCHEMBL29567963 | 0.76 | ACHE (0.62) | HTR6CYP2D6LMNADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103841-B | Substituted quinolinone piperazine compounds useful as T cell activators | 百时美施贵宝公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115103841-A | Substituted quinolinonyl piperazine compounds useful as T cell activators | 百时美施贵宝公司 | 2022-09-23 | — | — | CN | disclosed |