Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969192 | 0.88 | MTNR1A (0.34) | MTNR1AKDM4ELMNAMAPK1 | |
| SCHEMBL23969189 | 0.87 | MEN1 (0.36) | MTNR1AKDM4ECYP3A4LMNA | |
| SCHEMBL22176515 | 0.80 | MTNR1A (0.35) | MTNR1AADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL22175873 | 0.74 | — | — | |
| SCHEMBL22175855 | 0.74 | HTT (0.37) | LMNAMAPK1 | |
| SCHEMBL22175925 | 0.70 | MEN1 (0.36) | MTNR1AADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL22175847 | 0.69 | SIGMAR1 (0.40) | MTNR1AADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL22175941 | 0.68 | ALDH1A1 (0.39) | MTNR1AADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL23969348 | 0.67 | HTR1A (0.36) | KDM4E | |
| SCHEMBL22175888 | 0.66 | ALDH1A1 (0.41) | MTNR1AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903788-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2021-11-03 | — | — | EP | disclosed |