SCHEMBL2397289

SCHEMBL2397289

CCCOC(=O)CCP(C)(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.44
ADRA2A P08913 1/20 0.38
ADRA1A P35348 1/20 0.38
DNM1 Q05193 1/20 0.37
MAPT P10636 2/20 0.36
BLM P54132 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR2C P28335 1/20 0.36
ENPP2 Q13822 4/20 0.36
TRPV1 Q8NER1 1/20 0.36
POLB P06746 1/20 0.36
EPHX2 P34913 1/20 0.35
NAAA Q02083 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LPAR6 P43657 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR4 Q99677 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2397915 0.89 DGKA (0.50) DGKADNM1HTR2CENPP2TRPV1
SCHEMBL28390346 0.86 DGKA (0.45) DGKAADRA2AADRA1ADNM1MAPT
Butane SCHEMBL2238380 0.84 DGKA (0.44) DGKAADRA2AADRA1ADNM1MAPT
SCHEMBL4004473 0.84 MGLL (0.39) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL2397581 0.83 SMN1; SMN2 (0.49) SMN1; SMN2POLBALDH1A1
Ethylene Glycol SCHEMBL5407450 0.82 MGLL (0.38) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL29025936 0.81 DGKA (0.41) DGKAADRA2AADRA1ADNM1MAPT
SCHEMBL28392405 0.80 DGKA (0.44) DGKAADRA2AADRA1ADNM1MAPT
SCHEMBL2240315 0.78 DGKA (0.42) DGKAADRA2AADRA1ADNM1MAPT
SCHEMBL5707260 0.78 DGKA (0.42) DGKAADRA2AADRA1ADNM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160215123-A1 PHOSPHORUS-CONTAINING THERMOPLASTIC POLYESTER AND PHOSPHORUS-CONTAINING HEAT-SHRINKABLE TUBE MADE THEREFROM NAN YA PLASTICS CORPORATION (TW) 2016-07-28 US disclosed
CN-104761583-A METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID MEIJI SEIKA KAISHA 2015-07-08 CN disclosed
US-8017797-B2 Method for producing phosphorus-containing α-keto acid MEIJI SEIKA KAISHA LTD. (JP) 2011-09-13 US disclosed
US-20100063313-A1 METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID MEIJI SEIKA KAISHA LTD., (JP) 2010-03-11 US disclosed
CN-101641363-A Method for producing phosphorus-containing alpha-keto acid MEIJI SEIKA KAISHA JP 2010-02-03 CN disclosed
EP-2133356-A1 PROCESS FOR PRODUCTION OF PHOSPHORUS-CONTAINING -KETO ACID Meiji Seika Kaisha, Ltd. (JP) 2009-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063313-A1 METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID PRKAB1, PRKAB2, PLCB1 DGKA 494/4885ADRA2A 1651/4885ADRA1A 1653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.