SCHEMBL2397530

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2395880	0.89	ALDH1A1 (0.41)	ATRALDH1A1LMNARAB9AMAPT
	SCHEMBL27325719	0.84	MPO (0.43)	CTSLCTSSCTSKALDH1A1LMNA
	SCHEMBL2391854	0.83	ALDH1A1 (0.45)	ATRALDH1A1LMNARAB9AMAPT
	SCHEMBL2393300	0.80	GRM2 (0.50)	ALDH1A1CYP2C19ICMTL3MBTL1
	SCHEMBL2393136	0.79	SLC9A1 (0.42)	MAPTSMN1; SMN2CES2CES1ICMT
	SCHEMBL9890790	0.79	PKM (0.40)	ALDH1A1LMNARAB9AMAPTNPC1
	SCHEMBL9890745	0.79	CHRM1 (0.43)	ALDH1A1LMNARAB9AMAPTNPC1
	SCHEMBL9890738	0.79	ALDH1A1 (0.41)	ATRALDH1A1LMNARAB9AMAPT
	SCHEMBL2393938	0.78	KCNA5 (0.37)	ATRALDH1A1LMNARAB9ACES2
	SCHEMBL2397118	0.78	CHRM3 (0.44)	LMNASMN1; SMN2CYP2C19ICMTCXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.