Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978682 | 0.85 | LNPEP (0.42) | LNPEPITGB1ITGA5POLB | |
| SCHEMBL23978691 | 0.78 | PRMT5 (0.36) | ITGB1ITGA5TAS1R3TAS1R1NOS3 | |
| SCHEMBL30279430 | 0.77 | USP2 (0.49) | TAS1R3TAS1R1 | |
| SCHEMBL26494018 | 0.77 | USP2 (0.49) | TAS1R3TAS1R1 | |
| SCHEMBL23978656 | 0.77 | USP2 (0.49) | TAS1R3TAS1R1 | |
| SCHEMBL23978671 | 0.77 | USP2 (0.49) | TAS1R3TAS1R1 | |
| SCHEMBL23978644 | 0.77 | HPGD (0.45) | KDM4EPOLB | |
| SCHEMBL23978676 | 0.77 | KDM4E (0.33) | KDM4E | |
| SCHEMBL23978807 | 0.75 | ITGB2 (0.39) | ITGB1ITGA5KDM4EITGB2ICAM1 | |
| SCHEMBL26107828 | 0.75 | ITGB2 (0.39) | ITGB1ITGA5KDM4EITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |