Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978642 | 0.77 | LNPEP (0.39) | KDM4E | |
| SCHEMBL23978630 | 0.75 | FGFR1 (0.34) | — | |
| SCHEMBL23979131 | 0.69 | KCNQ2 (0.39) | LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30279379 | 0.67 | ABL1 (0.46) | KDM4ELMNAALDH1A1TSHRGAA | |
| SCHEMBL8295820 | 0.67 | ABL1 (0.46) | KDM4ELMNAALDH1A1TSHRGAA | |
| SCHEMBL23518398 | 0.66 | ITGB1 (0.38) | LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL23978682 | 0.65 | LNPEP (0.42) | ALDH1A1GAA | |
| SCHEMBL4593067 | 0.64 | L3MBTL1 (0.48) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10055986 | 0.63 | CA1 (0.50) | SMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL20050668 | 0.63 | PRKCZ (0.49) | KDM4ELMNASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |