Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992177 | 0.86 | HDAC1 (0.62) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL21096059 | 0.79 | SMN1; SMN2 (0.70) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4860120 | 0.77 | NPC1 (0.57) | KDM4ELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9979393 | 0.77 | CYP1A2 (0.55) | KDM4EHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL18160392 | 0.76 | L3MBTL1 (0.59) | NPC1RAB9ASMN1; SMN2GAATAS1R3 | |
| SCHEMBL169574 | 0.76 | ALOX15 (0.47) | KDM4ELMNARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL15296458 | 0.75 | ALDH1A1 (0.52) | KDM4ELMNAALDH1A1SMN1; SMN2THRB | |
| SCHEMBL4858193 | 0.75 | F10 (0.64) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL15886228 | 0.74 | NPC1 (0.59) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL24460185 | 0.74 | KCNMA1 (0.56) | KDM4ELMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219040-A1 | HISTONE DEACETYLASE INHIBITORS FOR IMMUNOMODULATION IN TUMOR MICROENVIRONMENT | GNT BIOTECH & MEDICALS CORPORATION (CN) | 2021-11-04 | — | — | WO | disclosed |