Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25478771 | 0.86 | HTR4 (0.33) | HTR7ALDH1A1 | |
| SCHEMBL25480336 | 0.86 | SIGMAR1 (0.36) | HTR7ALDH1A1 | |
| SCHEMBL25492876 | 0.85 | HTR7 (0.39) | HTR7 | |
| SCHEMBL25478772 | 0.85 | HTR7 (0.33) | HTR7KMT2AALDH1A1 | |
| SCHEMBL25628656 | 0.84 | L3MBTL1 (0.36) | HTR7KMT2ACHRNA7ALDH1A1 | |
| SCHEMBL24005863 | 0.84 | KMT2A (0.35) | HTR7KMT2ACHRNA7ALDH1A1 | |
| SCHEMBL25492808 | 0.84 | KMT2A (0.35) | HTR7KMT2ACHRNA7ALDH1A1 | |
| SCHEMBL25478784 | 0.84 | ALDH1A1 (0.35) | HTR7KMT2AALDH1A1 | |
| SCHEMBL25613556 | 0.82 | KMT2A (0.33) | HTR7KMT2ACHRNA7ALDH1A1 | |
| SCHEMBL24005860 | 0.82 | HTR2A (0.42) | HTR7KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088167-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-25 | — | — | WO | disclosed |
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |