Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480480 | 0.86 | ALDH1A1 (0.32) | ALDH1A1MAPK1MAPT | |
| SCHEMBL24005472 | 0.84 | HTR7 (0.36) | ALDH1A1HTR7KMT2A | |
| SCHEMBL25478771 | 0.82 | HTR4 (0.33) | ALDH1A1HTR7HTR1A | |
| SCHEMBL25480336 | 0.82 | SIGMAR1 (0.36) | ALDH1A1MAPK1HTR7DRD2 | |
| SCHEMBL25492876 | 0.81 | HTR7 (0.39) | HTR7HTR1ADRD2 | |
| SCHEMBL25478772 | 0.81 | HTR7 (0.33) | ALDH1A1HTR7HTR1ADRD2MEN1 | |
| SCHEMBL24405088 | 0.78 | ALDH1A1 (0.47) | ALDH1A1DRD2KMT2A | |
| SCHEMBL24005860 | 0.78 | HTR2A (0.42) | ALDH1A1HTR7OPRM1HTR1ADRD2 | |
| SCHEMBL25480501 | 0.78 | LMNA (0.48) | ALDH1A1MAPK1DRD2MEN1KMT2A | |
| SCHEMBL25480680 | 0.78 | SIGMAR1 (0.46) | DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088167-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-25 | — | — | WO | disclosed |