Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613563 | 0.82 | ALDH1A1 (0.42) | ALDH1A1POLBKDM4EBRD4CREBBP | |
| SCHEMBL24005504 | 0.81 | P2RX7 (0.41) | P2RX7ALDH1A1POLBNOTUMKMT2A | |
| SCHEMBL24333460 | 0.79 | P2RX7 (0.64) | P2RX7ALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL18913834 | 0.79 | P2RX7 (0.64) | P2RX7ALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL24333207 | 0.79 | P2RX7 (0.64) | P2RX7ALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL23323114 | 0.79 | KDM4E (0.50) | ALDH1A1POLBKDM4EBRD4CREBBP | |
| SCHEMBL24005505 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBKMT2AMAPTTDO2 | |
| SCHEMBL18711628 | 0.72 | SPR (0.44) | ALDH1A1POLBKDM4EBRD4CREBBP | |
| SCHEMBL23323068 | 0.72 | CHRNB2 (0.59) | — | |
| SCHEMBL23323095 | 0.72 | CHRNB2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |