Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613640 | 0.82 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HTR6TSHRNPSR1 | |
| SCHEMBL25480485 | 0.81 | L3MBTL1 (0.38) | ALDH1A1SMN1; SMN2TSHRNPSR1KDM1A | |
| SCHEMBL18913835 | 0.79 | CHRNB2 (0.49) | ALDH1A1SMN1; SMN2TSHRNPSR1RECQL | |
| SCHEMBL24333364 | 0.79 | CHRNB2 (0.49) | ALDH1A1SMN1; SMN2TSHRNPSR1RECQL | |
| SCHEMBL22213818 | 0.79 | CHRNB2 (0.49) | ALDH1A1SMN1; SMN2TSHRNPSR1RECQL | |
| SCHEMBL24005489 | 0.74 | P2RX7 (0.43) | ALDH1A1TDO2KMT2APOLBMAPT | |
| SCHEMBL23323068 | 0.72 | CHRNB2 (0.59) | — | |
| SCHEMBL23323095 | 0.72 | CHRNB2 (0.59) | — | |
| SCHEMBL23323096 | 0.72 | CHRNB2 (0.59) | — | |
| SCHEMBL24005491 | 0.69 | POLB (0.35) | NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |