Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3066792 | 0.85 | KDM4E (0.48) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27765071 | 0.83 | COPS5 (0.55) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3095838 | 0.83 | FBP1 (0.66) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL535765 | 0.80 | L3MBTL1 (0.56) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2442951 | 0.80 | KDM4E (0.51) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4166061 | 0.76 | KDM4E (0.59) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30200863 | 0.74 | FBP1 (0.46) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1096595 | 0.73 | ALDH1A1 (0.51) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29063447 | 0.72 | KDM4E (0.47) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28935913 | 0.71 | ALDH1A1 (0.60) | FBP1KDM4EALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101589024-B | Minor groove binders | UNIV STRATHCLYDE | 2014-01-01 | — | — | CN | disclosed |
| EP-2066627-B1 | NOVEL MINOR GROOVE BINDERS | UNIV STRATHCLYDE (GB) | 2013-10-23 | — | — | EP | disclosed |
| US-8012967-B2 | Minor groove binders | UNIVERSITY OF STRATHCLYDE (GB) | 2011-09-06 | — | — | US | disclosed |
| US-20100016311-A1 | NOVEL MINOR GROOVE BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2010-01-21 | — | — | US | disclosed |
| CN-101589024-A | Novel minor groove binders | UNIV STRATHCLYDE (GB) | 2009-11-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016311-A1 | NOVEL MINOR GROOVE BINDERS | TOP2B, DNA2, CTCF | FBP1 3015/4885KDM4E 1981/4885ALDH1A1 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.