Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011148 | 0.85 | RAB9A (0.54) | SIGMAR1CCR3RAB9AEPHX2POLB | |
| SCHEMBL13826421 | 0.78 | RBP4 (0.53) | SIGMAR1EPHX2LIPEPOLBALDH1A1 | |
| SCHEMBL26633717 | 0.76 | RAB9A (0.48) | SIGMAR1CCR3RAB9AEPHX2MEN1 | |
| SCHEMBL16002995 | 0.76 | RBP4 (0.55) | SIGMAR1EPHX2LIPEPOLBALDH1A1 | |
| SCHEMBL24011158 | 0.72 | NPC1 (0.57) | SIGMAR1CCR3RAB9AEPHX2ALDH1A1 | |
| SCHEMBL24011241 | 0.71 | CCR3 (0.60) | SIGMAR1CCR3RAB9AEPHX2ALDH1A1 | |
| SCHEMBL24011151 | 0.71 | NPC1 (0.58) | SIGMAR1CCR3RAB9AEPHX2MEN1 | |
| SCHEMBL24011682 | 0.70 | PRKAB2 (0.56) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL24011159 | 0.70 | SMN1; SMN2 (0.57) | SIGMAR1CCR3RAB9AEPHX2ALDH1A1 | |
| SCHEMBL24011556 | 0.70 | ACHE (0.49) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |