Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011602 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2EPHX2CHRM4P2RX7 | |
| SCHEMBL26633704 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2EPHX2CHRM4P2RX7 | |
| SCHEMBL24011682 | 0.74 | PRKAB2 (0.56) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15453396 | 0.70 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TSHRTDP1MAPT | |
| SCHEMBL24011270 | 0.70 | PKM (0.45) | ALDH1A1MAPTLMNA | |
| SCHEMBL24011567 | 0.70 | PKM (0.43) | ALDH1A1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL30924146 | 0.70 | ACKR3 (0.53) | ALDH1A1SMN1; SMN2EPHX2CHRM4P2RX7 | |
| SCHEMBL30924072 | 0.69 | EPHX2 (0.67) | ALDH1A1SMN1; SMN2EPHX2CHRM4 | |
| SCHEMBL24011702 | 0.69 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24011701 | 0.69 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |