Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011567 | 0.86 | PKM (0.43) | PKMALDH1A1KDM4EL3MBTL1MTNR1B | |
| SCHEMBL24011556 | 0.85 | ACHE (0.49) | ALDH1A1 | |
| SCHEMBL24011062 | 0.84 | SMN1; SMN2 (0.59) | PKMHRH3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24011413 | 0.82 | PKM (0.39) | PKMALDH1A1KDM4EL3MBTL1MTNR1B | |
| SCHEMBL3325902 | 0.81 | ALDH1A1 (0.53) | PKMHRH3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24011627 | 0.80 | MEN1 (0.46) | ALDH1A1KDM4EL3MBTL1MTNR1B | |
| SCHEMBL3327393 | 0.78 | HRH3 (0.58) | PKMHRH3ALDH1A1L3MBTL1 | |
| SCHEMBL3327390 | 0.78 | HRH3 (0.58) | PKMHRH3ALDH1A1L3MBTL1 | |
| SCHEMBL24011251 | 0.78 | ADAM17 (0.47) | HRH3ALDH1A1LMNA | |
| SCHEMBL24011636 | 0.78 | ADAM17 (0.46) | PKMHRH3ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |