SCHEMBL24040293

SCHEMBL24040293

Cc1ccc(O)c(C(CN)C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TRPA1 O75762 2/20 0.41
TP53 P04637 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 4/20 0.39
CHRM1 P11229 3/20 0.39
ADRA1A P35348 3/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2B P41595 1/20 0.39
MAPT P10636 3/20 0.38
CHRM2 P08172 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM3 P20309 2/20 0.38
HRH1 P35367 2/20 0.38
ESR1 P03372 1/20 0.38
CHRM4 P08173 1/20 0.38
KCNE1 P15382 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23868340 0.76 TRPA1 (0.48) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL13257345 0.71 TRPA1 (0.56) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL16168708 0.70 LMNA (0.52) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL9198019 0.70 LMNA (0.52) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL5596162 0.69 TRPA1 (0.45) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL4580619 0.69 GABRA1 (0.42) ALOX15HSD17B10ALDH1A1TRPA1TP53
Isothymol SCHEMBL852892 0.69 LMNA (0.68) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL50784 0.69 LMNA (0.56) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL218020 0.69 TRPA1 (0.54) ALOX15HSD17B10ALDH1A1TRPA1TP53
SCHEMBL30631004 0.69 TRPA1 (0.54) ALOX15HSD17B10ALDH1A1TRPA1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11180631-B2 Antioxidant composition SI GROUP USA (USAA), LLC (US) 2021-11-23 US disclosed