Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580619 | 0.91 | GABRA1 (0.42) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL5596162 | 0.84 | TRPA1 (0.45) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL13257345 | 0.78 | TRPA1 (0.56) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL16168708 | 0.77 | LMNA (0.52) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL24040293 | 0.76 | ALOX15 (0.41) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL218020 | 0.76 | TRPA1 (0.54) | TRPA1TDP1TP53LMNACHRM1 | |
| Isothymol SCHEMBL852892 | 0.76 | LMNA (0.68) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL30631004 | 0.76 | TRPA1 (0.54) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL50784 | 0.76 | LMNA (0.56) | TRPA1TDP1TP53LMNACHRM1 | |
| SCHEMBL27562673 | 0.76 | TRPA1 (0.54) | TRPA1TDP1TP53LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300853-A1 | ACCESS TO CHIRAL BISPHENOL (BPOL) LIGANDS THROUGH DESYMMETRIZING ASYMMETRIC ORTHO-SELECTIVE MONO-HALOGENATION | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2021-09-30 | — | — | US | disclosed |