Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23868340 | 0.84 | TRPA1 (0.48) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL5597005 | 0.79 | ALDH1A1 (0.53) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| SCHEMBL4580619 | 0.77 | GABRA1 (0.42) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL5596907 | 0.75 | TRPA1 (0.52) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL13257345 | 0.74 | TRPA1 (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL5596304 | 0.74 | GABRA1 (0.52) | TRPA1TP53TDP1LMNASLC6A2 | |
| SCHEMBL5595925 | 0.73 | ALDH1A1 (0.41) | TP53TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL50784 | 0.73 | LMNA (0.56) | TRPA1TP53TDP1LMNACHRM1 | |
| SCHEMBL218020 | 0.73 | TRPA1 (0.54) | TRPA1TP53TDP1LMNACHRM1 | |
| Isothymol SCHEMBL852892 | 0.73 | LMNA (0.68) | TRPA1TP53TDP1LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |