Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723371 | 0.96 | KDM4E (0.51) | CA1CA2CA12CA7CA9 | |
| SCHEMBL21854675 | 0.88 | KDM4E (0.42) | CA1CA2CA12CA7CA9 | |
| SCHEMBL15714872 | 0.84 | LOXL2 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13959913 | 0.83 | ATM (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13457142 | 0.83 | RAB9A (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13779116 | 0.82 | TDP1 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31271004 | 0.80 | GABRA1 (0.40) | CA1CA2CA12CA9CA14 | |
| SCHEMBL17071963 | 0.78 | MAPK1 (0.40) | KDM4ELMNAGAAALDH1A1MAPT | |
| SCHEMBL21637519 | 0.77 | POLB (0.45) | KDM4EPOLBLMNAGAAALDH1A1 | |
| SCHEMBL21348607 | 0.75 | CA1 (0.41) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939336-B2 | Aryl triazole cages | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-03-26 | — | — | US | disclosed |
| US-20210363150-A1 | ARYL TRIAZOLE CAGES | UNITED STATES DEPARTMENT OF ENERGY | 2021-11-25 | — | — | US | disclosed |
| US-20210363150-A1 | ARYL TRIAZOLE CAGES | UNITED STATES DEPARTMENT OF ENERGY | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939336-B2 | Aryl triazole cages | CAT, SOD1, SOD3 | CA1 1335/4885CA2 2748/4885CA12 1276/4885 |
| US-20210363150-A1 | ARYL TRIAZOLE CAGES | CAT, SOD1, SOD3 | CA1 1335/4885CA2 2748/4885CA12 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.