Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621908 | 0.76 | ACHE (0.40) | HSD11B1CYP3A4IDO1TDO2CES2 | |
| SCHEMBL31852251 | 0.75 | GABRA1 (0.50) | CYP3A4IDO1TDO2CES2CES1 | |
| SCHEMBL84442 | 0.75 | GABRA1 (0.50) | CYP3A4IDO1TDO2CES2CES1 | |
| SCHEMBL15903486 | 0.75 | ACHE (0.43) | HSD11B1CYP3A4IDO1TDO2CES2 | |
| SCHEMBL2401904 | 0.74 | CES2 (0.36) | CES2CES1ACHEALDH1A1GAA | |
| SCHEMBL2402247 | 0.74 | ESR1 (0.48) | CYP3A4ACHEALDH1A1CYP2C9GABRA1 | |
| SCHEMBL4199089 | 0.73 | GABRA1 (0.60) | CYP3A4MEN1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL2400168 | 0.73 | HSD11B1 (0.44) | HSD11B1CYP3A4IDO1TDO2ALDH1A1 | |
| SCHEMBL2400751 | 0.73 | HSD11B1 (0.44) | HSD11B1CYP3A4IDO1TDO2ALDH1A1 | |
| SCHEMBL2401009 | 0.72 | HSD11B1 (0.48) | HSD11B1IDO1TDO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835427-B2 | Fungicidal heterocyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-16 | — | — | US | disclosed |
| EP-2358709-B1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | DU PONT (US) | 2014-01-22 | — | — | EP | disclosed |
| US-8618137-B2 | Fungicidal heterocyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-06 | — | — | US | disclosed |
| US-20110224258-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (DE) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224258-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | NOX1, XDH, CBR1 | HSD11B1 426/4885CYP3A4 91/4885IDO1 226/4885 |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, NOX3, CYP1A1 | HSD11B1 424/4885CYP3A4 68/4885IDO1 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.