Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045704 | 0.83 | KDM1A (0.42) | PARP10PARP11CYP11B1CYP11B2HRH3 | |
| SCHEMBL24045876 | 0.80 | BACE1 (0.40) | PTGS2FAAHMGLLUSP2 | |
| SCHEMBL24045718 | 0.80 | BRD4 (0.46) | DHODHMGLLROCK2GRM2 | |
| SCHEMBL24045954 | 0.77 | POLB (0.33) | FAAHMGLLROCK2TSHR | |
| SCHEMBL24045868 | 0.77 | PTGS2 (0.44) | PTGS2FAAHMGLL | |
| SCHEMBL24045883 | 0.77 | FPR2 (0.40) | DHODHROCK2 | |
| SCHEMBL24045702 | 0.76 | DGAT1 (0.44) | DHODHHSD11B1GRM2CYP11B1CYP11B2 | |
| SCHEMBL24045802 | 0.76 | MAPT (0.34) | ROCK2HSD11B1HTR1A | |
| SCHEMBL24045932 | 0.75 | APP (0.47) | DHODHCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL24045705 | 0.75 | BCHE (0.38) | FAAHMGLLUSP2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |