Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 7/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045754 | 0.88 | UGCG (0.46) | UGCGNPC1RAB9AFPR2 | |
| SCHEMBL24045883 | 0.84 | FPR2 (0.40) | DYRK1ADHODHFPR2 | |
| SCHEMBL24045770 | 0.83 | UGCG (0.47) | UGCGNPC1RAB9AHTR2CHTR2B | |
| SCHEMBL24045766 | 0.80 | FPR1 (0.45) | BACE1FPR2 | |
| SCHEMBL24045702 | 0.78 | DGAT1 (0.44) | DHODHFPR2 | |
| SCHEMBL24045889 | 0.77 | S1PR1 (0.42) | UGCGDHODHFPR2 | |
| SCHEMBL24045911 | 0.76 | NAAA (0.40) | METAP2NPC1RAB9ADHODH | |
| SCHEMBL24045707 | 0.76 | DGAT1 (0.44) | BACE1NPC1RAB9A | |
| SCHEMBL24045718 | 0.74 | BRD4 (0.46) | BACE1DHODH | |
| SCHEMBL24045791 | 0.74 | CYP11B2 (0.38) | BACE1METAP2NPC1RAB9ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |