Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045868 | 0.86 | PTGS2 (0.44) | BACE1ALDH1A1HTTFAAHMGLL | |
| SCHEMBL24045957 | 0.86 | AOC3 (0.32) | BACE1ALDH1A1HTTFAAHMGLL | |
| SCHEMBL24045954 | 0.81 | POLB (0.33) | ALDH1A1HTTFAAHMGLLHSP90AA1 | |
| SCHEMBL24045892 | 0.80 | TAAR1 (0.45) | FAAHMGLLPTGS2USP2 | |
| SCHEMBL24045718 | 0.80 | BRD4 (0.46) | BACE1TGFBR1MGLLGAA | |
| SCHEMBL24045797 | 0.79 | PRMT6 (0.34) | BACE1F10 | |
| SCHEMBL24045704 | 0.77 | KDM1A (0.42) | — | |
| SCHEMBL24045719 | 0.75 | RAB9A (0.36) | ALDH1A1HTTFAAHMGLLPKM | |
| SCHEMBL24045796 | 0.75 | F10 (0.47) | BACE1ALDH1A1PKMLMNAGAA | |
| SCHEMBL24045705 | 0.72 | BCHE (0.38) | ALDH1A1HTTFAAHMGLLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |