Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391922 | 0.86 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL10391924 | 0.77 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11432522 | 0.76 | MAPK1 (0.49) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL27686558 | 0.75 | GAA (0.43) | KDM4EKMT2AMEN1HSD17B10HPGD | |
| SCHEMBL28057308 | 0.75 | POLB (0.46) | KMT2AMEN1MAPK1ALDH1A1TDP1 | |
| SCHEMBL2050907 | 0.73 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1156927 | 0.73 | KDM4E (0.70) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL8995261 | 0.72 | LMNA (0.48) | KDM4EKMT2AALDH1A1TDP1FOLH1 | |
| SCHEMBL143861 | 0.71 | HTT (0.53) | KDM4EKMT2AHSD17B10HPGDMAPK1 | |
| SCHEMBL29395127 | 0.71 | HTT (0.53) | KDM4EKMT2AHSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780961-B2 | Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof | ZHEJIANG UNIVERSITY (CN) | 2023-10-10 | — | — | US | disclosed |
| US-20210363297-A1 | ORGANIC METAL-FREE CATALYSTS WITH ELECTROPHILIC AND NUCLEOPHILIC DUAL-FUNCTIONS, PREPARATION METHODS OF MAKING THE SAME, AND USES THEREOF | ZHEJIANG UNIVERSITY (CN) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780961-B2 | Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof | DUOX1, SOD1, DUOX2 | KDM4E 3373/4885KMT2A 1593/4885MEN1 2218/4885 |
| US-20210363297-A1 | ORGANIC METAL-FREE CATALYSTS WITH ELECTROPHILIC AND NUCLEOPHILIC DUAL-FUNCTIONS, PREPARATION METHODS OF MAKING THE SAME, AND USES THEREOF | DUOX1, SOD1, DUOX2 | KDM4E 3373/4885KMT2A 1593/4885MEN1 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.