Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365484 | 0.79 | MAPT (0.61) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL8924902 | 0.79 | MAPT (0.61) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL10367206 | 0.78 | MAPT (0.62) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL8578207 | 0.77 | GAA (0.59) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL24050095 | 0.76 | GAA (0.48) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL25724853 | 0.76 | ALDH1A1 (0.33) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL2267690 | 0.75 | MAPT (0.57) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL19685318 | 0.73 | MAPT (0.55) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL2491643 | 0.73 | MAPT (0.67) | GAAMAPTTSHRALDH1A1TP53 | |
| SCHEMBL5965069 | 0.72 | MAOA (0.44) | TSHRALDH1A1TP53SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3713927-B1 | PYRIDINONE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS | NOVARTIS AG (CH) | 2021-12-15 | — | — | EP | disclosed |
| WO-2021236489-A1 | BIOMASS DERIVED DIKETONES AS EFFICIENT VISIBLE LIGHT PHOTOINITIATORS | BOWLING GREEN STATE UNIVERSITY (US) | 2021-11-25 | — | — | WO | disclosed |