SCHEMBL2406498

SCHEMBL2406498

O=C1NOC2=CC=CCC2=C1c1ccccc1C1=C2CC=CC=C2ONC1=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.33
ALDH1A1 P00352 1/20 0.31
CASP3 P42574 1/20 0.30
CASP2 P42575 1/20 0.30
CASP7 P55210 1/20 0.30
CASP6 P55212 1/20 0.30
CASP8 Q14790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1853354 0.72
Hydrochloric Acid SCHEMBL6411559 0.64 PKM (0.36) ALDH1A1
SCHEMBL6114440 0.62 CDC25B (0.35) ALDH1A1
SCHEMBL10517673 0.61 GSK3B (0.38) GSK3BALDH1A1CASP3CASP2CASP7
SCHEMBL6266516 0.60 KDM4E (0.32)
Phthalimide SCHEMBL28372975 0.57 GSK3B (0.83) GSK3BALDH1A1CASP3CASP2CASP7
SCHEMBL737866 0.57 MAOA (0.41) GSK3BALDH1A1
SCHEMBL787044 0.56 CDC25B (0.55) ALDH1A1CASP3CASP2CASP7CASP6
SCHEMBL30626777 0.56
SCHEMBL28006187 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3709966-B1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT OREAL (FR) 2024-12-11 EP claimed
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'OREAL (FR) 2020-11-19 US claimed
EP-3709966-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'Oreal (FR) 2020-09-23 EP claimed
CN-111343968-A Composition comprising at least one acrylic polymer and at least one insoluble organic masking agent 莱雅公司 2020-06-26 CN claimed
CN-105705131-B Cosmetic or dermatological composition comprising a merocyanine and a UV-screening agent 莱雅公司 2019-12-17 CN claimed
EP-2945602-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'ORÉAL (FR) 2018-01-10 EP claimed
EP-2945602-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'Oréal (FR) 2015-11-25 EP claimed
EP-2872107-A1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES L'Oréal (FR) 2015-05-20 EP claimed
WO-2014111566-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'OREAL (FR) 2014-07-24 WO claimed
WO-2014010099-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARING THE SAME L'OREAL (FR) 2014-01-16 WO claimed
US-6818206-B2 CONTROLLING PARTICLE SIZES; TOPICAL APPLYING L'OREAL (FR) 2004-11-16 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-1370232-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2003-12-17 EP claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
US-20030129151-A1 Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them L'OREAL (FR) 2003-07-10 US claimed
EP-1317918-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2003-06-11 EP claimed
EP-1302197-A1 Use of amphiphilic copolymers to stabilise dispersions of non-soluble organic compounds filtering UV light L'OREAL (FR) 2003-04-16 EP claimed
WO-2002056858-A1 SOLAR PROTECTION COMPOSITIONS L'OREAL (FR) 2002-07-25 WO claimed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129151-A1 Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them CUTA, HNRNPU, ERCC5 GSK3B 3819/4885ALDH1A1 1823/4885CASP3 1656/4885
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT PCNA, ERCC1, XRCC6 GSK3B 4855/4885ALDH1A1 683/4885CASP3 1096/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD GSK3B 2485/4885ALDH1A1 246/4885CASP3 1473/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 GSK3B 2290/4885ALDH1A1 193/4885CASP3 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.